Drug Testing in Greenville, South Carolina

US Drug Test Centers has more than 20,000 testing locations nationwide. We offer drug and alcohol testing in Greenville, South Carolina for both Department of Transportation (DOT) and non-DOT companies, along with individuals. We provide affordable urine drug testing, hair follicle drug testing, breath alcohol tests, and more in Greenville. We only work with SAMHSA-certified laboratories, and all test results are verified by a medical review officer (MRO).

Order a test online or call 866-566-0261 for more help.

Representative image for Greenville, South Carolina

Committed to Accuracy

We only work with SAMHSA-certified laboratories and have all test results confirmed by a medical review officer.

Unparalleled Convenience

With drug testing locations spread throughout Greenville, South Carolina, you never have to go far to find us. For speedy results, we offer instant urine drug testing and on-site mobile testing.

Endless Variety

We can screen for dozens of illicit substances via hair, urine, and breath. Additionally, we have hundreds of drug test panels to choose from.

49 Testing locations in Greenville, South Carolina

3535 Pelham Rd

Greenville, South Carolina 29615

Phone: 866-566-0261

135 Commonwealth Dr

Greenville, South Carolina 29615

Phone: 866-566-0261

503 Roper Creek Dr

Greenville, South Carolina 29615

Phone: 866-566-0261

41 Park Creek Dr

Greenville, South Carolina 29605

Phone: 866-566-0261

2498 N Pleasantburg Drive

Greenville, South Carolina 29609

Phone: 866-566-0261


44 more location(s) available in Greenville , South Carolina

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Reviews From Customers in Greenville, South Carolina

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Review by K.K.K.H.
on January 5, 2023

"Some of the sites we send candidates to for pre-employment drug screens to, the candidates are made to wait for long periods. Even when they call to get a designated time. And the price increase is a little much"

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US Drug Test Centers

US Drug Test Centers

We are your complete drug-free workplace solution for employers. We provide drug testing for all reasons such as pre-employment, random, reasonable suspicion, post-accident, and return to duty. We have a state-of-the-art cloud-based software that allows you to order drug testing 24/7, store all drug test results and chain of custody forms (forever), and you can see the status of all completed drug testing. We have random drug and alcohol testing consortiums and follow all DOT rules and regulations to direct your company in the right direction to stay in compliance. We can create drug-free workplace policy manuals specific to your company's needs, and we provide online trainings. Our online trainings are perfect for company Supervisors to learn what signs to look for if someone might be under the influence. We also have trainings that explain what Supervisors should know about the DOT rules and regulations in regards to the drug and alcohol testing program. We are a part of the Drug and Alcohol Testing Industry Association (DATIA), and we always stay up to date with all drug testing-related rules and regulations. If you have any questions about state-specific laws regarding drug and alcohol testing, please contact our office and one of our team members will be glad to help you. If your company would like more information regarding setting up a corporate account you can set up an account online or contact us at 866-566-0261.

Frequently Asked Questions About South Carolina Drug Testing

This material is intended for informational purposes only and should not be relied upon for legal guidance. State & local laws change frequently and vary greatly. These are state & local laws and do not over rule the federal Department of Transportation laws & policies. Readers are advised to consult with their legal counsel or industry experts before acting based on this information. Last Updated Jul 2023

South Carolina Drug Testing FAQs

Do employers in South Carolina need to comply with mandatory state-specific rules when drug & alcohol testing?
No. South Carolina does not have any mandatory drug testing statutes or regulations but it is recommended.
Is a Drug-Free Workplace policy required in South Carolina?
No, however, employers are strongly encouraged to have a written policy in place in general. Employers that receive state contracts are required to implement a drug-free workplace program.  (Policy is specifically required to comply with the states’ voluntary law).
Are employers in South Carolina able to leverage their drug screening program to reduce their Worker’s Compensation Insurance costs?
Yes. This state provides employers with the ability to voluntarily participate in a Drug-Free Workplace Program to qualify for workers’ compensation insurance premium reductions. Employers wishing to leverage these benefits must voluntarily comply with very detailed program rules.
Are employers in South Carolina able to use drug screening for any other claim defenses or state-specific financial benefits?
Yes. Employers may be able to leverage an ‘Intoxication’ defense to a Workers’ Compensation Claim, based on a positive drug test result. A positive drug test or refusal to test may also make an employee ineligible for unemployment compensation when terminated for misconduct. Employers wishing to leverage either of these benefits must voluntarily comply with very detailed program rules.
What are some nuances of the voluntary Drug-Free Workplace Program requirements in South Carolina?
Employers are required to have a written policy. The policy must specify testing procedures and maintain confidentiality. Employers must provide notice of the policy to employees.
Does South Carolina authorize marijuana (THC) or cannabidiol (CBD) use?
Yes. South Carolina authorizes the medical use of cannabidiol (CBD) for very limited medical conditions. The law does not address the workplace.
Can I be fired or lose a job offer in South Carolina if I fail a drug test?
In South Carolina, if you test positive on a drug test it can be grounds for termination or a rescinded job offer.

Drug Testing Stats - Greenville, South Carolina

Drug and Alcohol Abuse Statistics from Greenville, South Carolina

Last Updated: February 6, 2024

  • In South Carolina, 246 patients are in the hospital dealing with substance abuse problems resulting in rehab.
  • In South Carolina, there are 8 drug rehab facilities that provide free treatment for all clients.
  • There was an increase in deaths per capita related to alcohol abuse and binge drinking in South Carolina between 2015 and 2019 that caused a 53.40% increase.
  • In South Carolina, there are 17.10% more opioid overdoses that happen each year.
  • Studies show that in South Carolina, in a 1 year period 35,600 people who used a needle for drug habits had Hepatitis C.

South Carolina’s Substance Abuse Problem

In South Carolina, an average of approximately 2,586 deaths are attributable to excessive alcohol consumption. Additionally, 1,127 people will die from a drug overdose each and every year. The opioid epidemic is present in South Carolina, as well, with 835 opioid overdose deaths annually.

The Financials of Rehab

The U.S. public expenditure on outpatient drug rehabilitation services is approximately 1.46% or $33.73 million. Rehab isn’t cheap for those who need treatment, adding up to about $57,774 per individual for inpatient treatment and $1,707 for outpatient rehabilitation.


  1. The National Survey on Drug Use and Health (NSDUH), conducted annually by the Substance Abuse and Mental Health Services Administration (SAMHSA)
  2. Provisional Multiple Cause of Death database contains mortality and population for U.S. counties.
  3. Alcohol Use in the United States: Age Groups and Demographic Characteristics

Available Collection Types

US Drug Test Centers offers the full range of collection types, including urine, hair and breath samples, each with its own advantages and applications for accurate substance screening.

Legal Drug Testing

Legal drug testing is a critical procedure often mandated by employers, law enforcement agencies, and organizations to ensure compliance with regulations and maintain safety in various settings. US Drug Test Centers can help you with your testing needds.

DOT Testing Services

DOT Testing Services are specifically designed to meet the stringent drug and alcohol testing requirements mandated by the U.S. Department of Transportation (DOT) for safety-sensitive positions in the transportation industry, ensuring compliance and public safety.

Laboratory Testing Services

Looking for nationwide laboratory testing? US Drug Test Centers has partnered with eNational Testing to offer laboratory testing such as blood titers (MMR, Varicella, Hep B), QuantiFERON (TB Blood) Testing, Mens & Womens health panels, allergy testing and much more! You can simply order a health lab test or panel online 24/7 and go in for testing the same day at over 2,700 locations nationwide.

Scheduling your preventative health laboratory testing in Greenville, South Carolina here.

Our Drug Testing Partners