South Carolina Drug Testing

US Drug Test Centers works with South Carolina employers, employees, and residents to provide a wide range of drug and alcohol testing services. Keep reading to learn more about how we're helping in the fight against substance abuse with affordable and reliable drug testing.

Our testing locations do not accept payment and require a drug test order form at the time of testing. Please click the "Order a Test" button to order your test. Once your order has been processed, your drug test order form will be emailed to you. Testing options may vary on a site by site basis. Additional fees may apply depending on your location.

Committed to Accuracy

We only work with SAMHSA-certified laboratories and have all test results confirmed by a medical review officer.

Unparalleled Convenience

With drug testing locations spread throughout South Carolina, you never have to go far to find us. For speedy results, we offer instant urine drug testing and on-site mobile testing.

Endless Variety

We can screen for dozens of illicit substances via hair, urine, and breath. Additionally, we have hundreds of drug test panels to choose from.

521 Testing locations in South Carolina

122 Okatie Center Blvd S North

Okatie South Carolina 29909

Phone: 866-566-0261

14866 Ocean Hwy

Pawleys Island South Carolina 29585

Phone: 866-566-0261

729 Crossroads Plaza

Fort Mill South Carolina 29708

Phone: 866-566-0261

145 Executive Dr

Newberry South Carolina 29108

Phone: 866-566-0261

550 S Church St

Spartanburg South Carolina 29306

Phone: 866-566-0261


516 more location(s) available in South Carolina

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Local Reviews

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Review by D.F.
on April 5, 2023

"Very professional and friendly at the same time"

Review by L.W.
on February 16, 2023

"Excellent service and communication. Highly recommend!"

Review by M.P.
on February 6, 2023

"Quick, efficient and the technician was extremely helpful and very friendly."

Review by G.R.
on January 31, 2023

"They are thorough and reliable...... Thanks!"

Review by K.K.K.H.
on January 5, 2023

"Some of the sites we send candidates to for pre-employment drug screens to, the candidates are made to wait for long periods. Even when they call to get a designated time. And the price increase is a little much"

Review by A.F.
on December 22, 2022


Review by W.B.
on August 29, 2022


US Drug Test Centers

US Drug Test Centers

We are your complete drug-free workplace solution for employers. We provide drug testing for all reasons such as pre-employment, random, reasonable suspicion, post-accident, and return to duty. We have a state-of-the-art cloud-based software that allows you to order drug testing 24/7, store all drug test results and chain of custody forms (forever), and you can see the status of all completed drug testing. We have random drug and alcohol testing consortiums and follow all DOT rules and regulations to direct your company in the right direction to stay in compliance. We can create drug-free workplace policy manuals specific to your company's needs, and we provide online trainings. Our online trainings are perfect for company Supervisors to learn what signs to look for if someone might be under the influence. We also have trainings that explain what Supervisors should know about the DOT rules and regulations in regards to the drug and alcohol testing program. We are a part of the Drug and Alcohol Testing Industry Association (DATIA), and we always stay up to date with all drug testing-related rules and regulations. If you have any questions about state-specific laws regarding drug and alcohol testing, please contact our office and one of our team members will be glad to help you. If your company would like more information regarding setting up a corporate account you can set up an account online or contact us at 866-566-0261.

Frequently Asked Questions About South Carolina Drug Testing

This material is intended for informational purposes only and should not be relied upon for legal guidance. State & local laws change frequently and vary greatly. These are state & local laws and do not over rule the federal Department of Transportation laws & policies. Readers are advised to consult with their legal counsel or industry experts before acting based on this information. Last Updated Apr 2023

South Carolina Drug Testing FAQs

Do employers in South Carolina need to comply with mandatory state-specific rules when drug & alcohol testing?
No. South Carolina does not have any mandatory drug testing statutes or regulations but it is recommended.
Is a Drug-Free Workplace policy required in South Carolina?
No, however, employers are strongly encouraged to have a written policy in place in general. Employers that receive state contracts are required to implement a drug-free workplace program.  (Policy is specifically required to comply with the states’ voluntary law).
Are employers in South Carolina able to leverage their drug screening program to reduce their Worker’s Compensation Insurance costs?
Yes. This state provides employers with the ability to voluntarily participate in a Drug-Free Workplace Program to qualify for workers’ compensation insurance premium reductions. Employers wishing to leverage these benefits must voluntarily comply with very detailed program rules.
Are employers in South Carolina able to use drug screening for any other claim defenses or state-specific financial benefits?
Yes. Employers may be able to leverage an ‘Intoxication’ defense to a Workers’ Compensation Claim, based on a positive drug test result. A positive drug test or refusal to test may also make an employee ineligible for unemployment compensation when terminated for misconduct. Employers wishing to leverage either of these benefits must voluntarily comply with very detailed program rules.
What are some nuances of the voluntary Drug-Free Workplace Program requirements in South Carolina?
Employers are required to have a written policy. The policy must specify testing procedures and maintain confidentiality. Employers must provide notice of the policy to employees.
Does South Carolina authorize marijuana (THC) or cannabidiol (CBD) use?
Yes. South Carolina authorizes the medical use of cannabidiol (CBD) for very limited medical conditions. The law does not address the workplace.
Can I be fired or lose a job offer in South Carolina if I fail a drug test?
In South Carolina, if you test positive on a drug test it can be grounds for termination or a rescinded job offer.

Drug Testing Stats - South Carolina

Drug and Alcohol Abuse Statistics from South Carolina

Last Updated: March 1, 2024

  • Statistics show that in South Carolina, 0.6% or $31.14 million is spent on inpatient rehab facilities to help those who need assistance in drug and alcohol recovery.
  • Alcohol excessive use in South Carolina is the cause of 1 death per every 1,979 people each year.
  • 82.70% of adults 35 and older in South Carolina died from excessive alcohol use.
  • Each year in South Carolina, 17.0 of every 100,000 residents living there's cause of death is opioid overdose.
  • 1.60% of people in South Carolina had a reported overdose death.
  • 66.6% of employers enrolled into the Clearinghouse in South Carolina received a violation.

The Rise of Substance Abuse in South Carolina

In the state of South Carolina, 16.30% of adults over the age of 18 binge drink at least once a month. The CDC estimates that there are 66,458 years of potential life lost to excessive alcohol use every single year. Everyone pays the price, literally. In 2010, South Carolina taxpayers spent approximately $3.983 billion as a result of excessive alcohol use. Drug abuse is equally damaging, causing 1,127 overdose deaths each year.

Seeking Help for Drug and Alcohol Use

South Carolina has roughly 126 active rehabilitation clinics serving about 20,539 clients annually. An individual in outpatient rehab can expect to pay around $1,707 for their treatment. For residential rehab programs, on the other hand, the average expense in South Carolina is $57,774. Only 8 clinics offer free drug rehab for all clients, meaning addiction is expensive to conquer.


  1. The National Survey on Drug Use and Health (NSDUH), conducted annually by the Substance Abuse and Mental Health Services Administration (SAMHSA)
  2. Provisional Multiple Cause of Death database contains mortality and population for U.S. counties.
  3. Alcohol Use in the United States: Age Groups and Demographic Characteristics
  4. United States Department of Transportation - FMCSA Drug and Alcohol Clearinghouse - December 2023 Report

Workplace Drug Testing for South Carolina Companies

We work with both Department of Transportation (DOT) and non-DOT companies to help South Carolina employers maintain a drug-free workplace.

US Drug Test Centers can conduct drug tests of all kinds, including reasonable suspicion drug testing, random testing, pre-employment drug screening, post-accident drug screening, and return-to-duty drug testing. We can test for drug abuse via hair, urine, and breath specimens.

Plus, we provide drug testing policies for businesses in South Carolina. Drug testing policies cover vital details such as what type of drug screening you conduct, what illegal drugs you test for, what happens should an employee receive a positive drug test result, how you comply with federal law, the company's stance on medical marijuana, and what counts as "reasonable suspicion."

Furthermore, we offer employee training so that these individuals can help the employer manage the drug-free workplace program. They'll learn how to order drug tests, how to determine reasonable suspicion, and so much more.

Learn more about our employment testing and services.

If you're a DOT company or owner-operator, we'll help you stay compliant with federal and state law. Learn more about our DOT testing and services.

Beach in South Carolina

What Makes US Drug Test Centers Different?

With other drug and alcohol testing providers in South Carolina, why should you partner with US Drug Test Centers? What makes our drug screening different?

Accurate Drug Test Results

Reliable results are of critical importance.

We work with SAMHSA-certified (Substance Abuse and Mental Health Services Administration) laboratories. These labs are held to very strict standards regarding their equipment and processes, ensuring accurate test results.

Furthermore, all test results are verified by a medical review officer (MRO), who is a licensed physician. Why is a medical review officer important?

Let's say, for example, an employee receives a positive drug test result but thinks it was triggered by their prescribed medications. A medical review officer can confirm the validity of the drug test results and determine if follow-up drug screening is needed.

Convenient Drug and Alcohol Testing

Ordering a drug test has never been this easy. With more than 20,000 locations nationwide, you won't have a hard time finding us in South Carolina. Some of our locations even offer same-day service.

Do you need drug or alcohol testing in a hurry? We offer instant/POCT urine drug testing, which returns negative results the same day.

We also provide onsite mobile drug testing. A trained collector will meet you or your employee within two hours to begin the collection process.

Charleston, South Carolina

An Endless Variety of Drug Tests

We carry the most comprehensive selection of drug tests available. Our drug screening covers illegal substances including marijuana, cocaine, PCP, ecstasy, steroids, suboxone, Rohypnol, methadone, barbiturates, and many others.

Choose a drug test panel, which will combine multiple controlled substances. If you don't see the panel you're looking for on our website, contact us and we'll be happy to assist you!

Stellar Customer Service

Our drug testing specialists are standing by to assist you. Whether you need guidance while ordering a drug test, information about having a drug testing policy South Carolina, or information on working with a medical review officer, we're here to support you.

Order a Drug Test in South Carolina Today

Whether you're an employer who needs drug and alcohol testing, a parent concerned that their teenager is engaging in drug use, or a DOT company who needs drug screening for employees in safety-sensitive positions, US Drug Test Centers can help.

When we work together, we can keep substance abuse out of South Carolina. Companies can enjoy a drug-free workplace; communities can keep drug abuse out; and families can stay safe from illegal drug use.

Drug testing has never been more important.

Ready to take the next step? Order a test today!

Available Collection Types

US Drug Test Centers offers the full range of collection types, including urine, hair and breath samples, each with its own advantages and applications for accurate substance screening.

Legal Drug Testing

Legal drug testing is a critical procedure often mandated by employers, law enforcement agencies, and organizations to ensure compliance with regulations and maintain safety in various settings. US Drug Test Centers can help you with your testing needds.

DOT Testing Services

DOT Testing Services are specifically designed to meet the stringent drug and alcohol testing requirements mandated by the U.S. Department of Transportation (DOT) for safety-sensitive positions in the transportation industry, ensuring compliance and public safety.

Our Drug Testing Partners