South Dakota Drug Testing

Methamphetamine and heroin have no boundaries when it comes to South Dakota metropolitan and rural communities. With a rise in overdoses since 2015, these two culprits continue to be the most common drugs used in the state. In the past 5 years hospitals have reported an increase in opioid related cases and on average most South Dakota residents repot a higher level of alcohol intake than the national average.

US Drug Test Centers have 84 locations in South Dakota and aim to be here for residents and visitors in need of information about drug and alcohol testing. With the statistics rising, it is vital that the community knows where to obtain drug and alcohol tests that can be done quickly and accurately. Most of our locations are open daily. You can also call to speak to a representative about your drug and alcohol testing needs.

We offer ETG and DOT testing as well as 5 and 10 panel screenings. If you need a test for work or personal reasons, we have your drug and alcohol testing need taken care of. Find more information about online drug tests on our website.

Our testing locations do not accept payment and require a drug test order form at the time of testing. Please click the "Order a Test" button to order your test. Once your order has been processed, your drug test order form will be emailed to you. Testing options may vary on a site by site basis. Additional fees may apply depending on your location.

Committed to Accuracy

We only work with SAMHSA-certified laboratories and have all test results confirmed by a medical review officer.

Unparalleled Convenience

With drug testing locations spread throughout South Dakota, you never have to go far to find us. For speedy results, we offer instant urine drug testing and on-site mobile testing.

Endless Variety

We can screen for dozens of illicit substances via hair, urine, and breath. Additionally, we have hundreds of drug test panels to choose from.

42 Testing locations in South Dakota

2116 Jackson Blvd

Rapid City South Dakota 57702

Phone: 866-566-0261

370 3Rd St

Stratford South Dakota 57474

Phone: 866-566-0261

1445 North Ave Ste 2

Spearfish South Dakota 57783

Phone: 866-566-0261

900 East 54th St. North, Suite 200

Sioux Falls South Dakota 57104

Phone: 866-566-0261

7600 S Minnesota Avenue

Sioux Falls South Dakota 57108

Phone: 866-566-0261


37 more location(s) available in South Dakota

Artboard 10 Swipe to see more

US Drug Test Centers

US Drug Test Centers

We are your complete drug-free workplace solution for employers. We provide drug testing for all reasons such as pre-employment, random, reasonable suspicion, post-accident, and return to duty. We have a state-of-the-art cloud-based software that allows you to order drug testing 24/7, store all drug test results and chain of custody forms (forever), and you can see the status of all completed drug testing. We have random drug and alcohol testing consortiums and follow all DOT rules and regulations to direct your company in the right direction to stay in compliance. We can create drug-free workplace policy manuals specific to your company's needs, and we provide online trainings. Our online trainings are perfect for company Supervisors to learn what signs to look for if someone might be under the influence. We also have trainings that explain what Supervisors should know about the DOT rules and regulations in regards to the drug and alcohol testing program. We are a part of the Drug and Alcohol Testing Industry Association (DATIA), and we always stay up to date with all drug testing-related rules and regulations. If you have any questions about state-specific laws regarding drug and alcohol testing, please contact our office and one of our team members will be glad to help you. If your company would like more information regarding setting up a corporate account you can set up an account online or contact us at 866-566-0261.

Frequently Asked Questions About South Dakota Drug Testing

This material is intended for informational purposes only and should not be relied upon for legal guidance. State & local laws change frequently and vary greatly. These are state & local laws and do not over rule the federal Department of Transportation laws & policies. Readers are advised to consult with their legal counsel or industry experts before acting based on this information. Last Updated Feb 2023

South Dakota Drug Testing FAQs

Do employers in South Dakota need to comply with mandatory state-specific rules when drug & alcohol testing?
No. This South Dakota does not have any mandatory drug testing statutes or regulations but it is recommended.
Is a Drug-Free Workplace policy required in South Dakota?
No, however, employers are strongly encouraged to have a written policy in place (Policy is specifically required to comply with the South Dakota’s voluntary law).
Are employers in South Dakota able to use drug screening for any other claim defenses or state-specific financial benefits?
Yes. Employers may be able to leverage an ‘Intoxication’ defense to a Workers’ Compensation Claim, based on a positive drug test result and misconduct. A positive drug test or refusal to test may also make an employee ineligible for unemployment compensation. Employers wishing to leverage either of these benefits must voluntarily comply with very detailed program rules.
Does South Dakota authorize marijuana (THC) or cannabidiol (CBD) use?
Yes. South Dakota authorizes the medical use of cannabidiol (CBD) for very limited medical conditions. The law does not address the workplace.
Can I be fired or lose a job offer in South Dakota if I fail a drug test?
In South Dakota, if you test positive on a drug test it can be grounds for termination or a rescinded job offer.
What are the medical and recreational marijuana-related rules in South Dakota?
In South Dakota, medical marijuana use is considered legal and cannot be used against you if you test positive, unless you are in a safety sensitive position.

Drug Testing Stats - South Dakota

Drug and Alcohol Abuse Statistics from South Dakota

Last Updated: February 6, 2024

  • Each year in South Dakota, there are approximately 2,346 patients who check themselves into an outpatient drug rehab program.
  • In South Dakota, 25% of most active drinkers consume 8 alcoholic beverages per binge.
  • Studies have shown that in South Dakota, 66.10% of males who binge drink are more likely to lose their life due to binge drinking alcohol.
  • In South Dakota, there was an increase by 11.53% of deaths caused by drug overdose in the last 3 years.
  • Each year in South Dakota, 10.5 of every 100,000 residents living there's cause of death is drug overdose.

The Rise of Substance Abuse in South Dakota

In the state of South Dakota, 22.30% of adults over the age of 18 binge drink at least once a month. The CDC estimates that there are 12,203 years of potential life lost to excessive alcohol use every single year. Everyone pays the price, literally. In 2010, South Dakota taxpayers spent approximately $598.2 million as a result of excessive alcohol use. Drug abuse is equally damaging, causing 86 overdose deaths each year.

Seeking Help for Drug and Alcohol Use

South Dakota has roughly 64 active rehabilitation clinics serving about 2,864 clients annually. An individual in outpatient rehab can expect to pay around $1,969 for their treatment. For residential rehab programs, on the other hand, the average expense in South Dakota is $56,108. Only 3 clinics offer free drug rehab for all clients, meaning addiction is expensive to conquer.


  1. The National Survey on Drug Use and Health (NSDUH), conducted annually by the Substance Abuse and Mental Health Services Administration (SAMHSA)
  2. Provisional Multiple Cause of Death database contains mortality and population for U.S. counties.
  3. Alcohol Use in the United States: Age Groups and Demographic Characteristics

Finding a Drug Test Center Near You

US Drug Tests Centers can be found in all major cities in South Dakota, with 12 locations in Sioux Falls including one adjacent to the Avera McKennan Hospital and University in zip codes 57105, 57104, 57106, 57108 and 57110. We also have locations in Aberdeen (4), Brookings (3 including one less than 4 minutes form the Brookings Regional hospital), Watertown (4). If you are planning a trip to Mount Rushmore and need a test during your travels we have locations in Custer 19.7 miles south and 11 in Rapid City, Pennington County, zip codes 57701 and 57702.

Drug Free Workplace Program

For employers US Drug Test Centers can help provide a comprehensive drug free workplace program including employee drug testing. Both DOT and non-DOT programs are available for complete compliance with Federal, State and local regulations. US Drug Testing Center works with businesses of all types, with an emphasis on industries where the substance abuse challenges are the greatest.

Comprehensive drug free workplace programs include:

  • A Written Substance Abuse Policy
  • Employee Awareness and Education
  • Supervisor Training
  • An Employee Assistance Plan of Action
  • Drug and Alcohol Testing

US Drug Test Centers provides effective drug-free program consisting of the five elements listed above that, together, provide a full, comprehensive management and training program designed specifically to meet the needs of your company. US Drug Test Centers can help your company get started with a drug-free program that's right for you, or help you put in place the right processes for maintaining your program, depending upon your specific situation.

South Dakota Laws on Drug Testing

South Dakota has no law restricting or prohibiting drug testing by private employers. South Dakota law does not address drug testing in private employment. This means that private employers are not prohibited or restricted from drug testing applicants and employees.

Immediate Testing

All US Drug Testing Center locations are able to provide immediate drug and alcohol testing for individuals and employers, when the situation requires immediate testing with expedited results. Immediate testing means that the testing itself is done same-day, or immediately, with the results usually reported back the next business day. This immediate drug and alcohol testing is available for situations such as:

Many attorneys in South Dakota work with our US Drug Test Centers to order probation & court ordered drug and or alcohol tests for their clients.

For individuals, personal drug and alcohol testing is always available with same day service. Our testing programs include:

Do you need a drug test today in the State of South Dakota? US Drug Test Centers is a nationwide company with locations throughout SOUTH DAKOTA for drug and alcohol testing. Drug and alcohol testing with immediate service is available for individuals for personal drug tests and for employers for employee drug testing.

Call now 1-866-566-0261 for service at any of our many facilities in the State of South Dakota.

In South Dakota, US Drug Test Centers has facilities throughout the State in all cities, with multiple facilities in Sioux Falls, Rapid City, Aberdeen, Brookings, Watertown, Yankton, Pierre, Huron and Vermillion.

About South Dakota

From the Badlands to Mount Rushmore, South Dakota has no shortage of places to visit. For visitors who enjoy fishing, exploring caves or visiting historical landmarks, South Dakota does not disappoint. With a population of South Dakota under 900,000 and the majority of its residents living in Buffalo County, South Dakota, like other Midwest states, caters to a large rural population of towns with less than 3,000 residents.

Available Collection Types

US Drug Test Centers offers the full range of collection types, including urine, hair and breath samples, each with its own advantages and applications for accurate substance screening.

Legal Drug Testing

Legal drug testing is a critical procedure often mandated by employers, law enforcement agencies, and organizations to ensure compliance with regulations and maintain safety in various settings. US Drug Test Centers can help you with your testing needds.

DOT Testing Services

DOT Testing Services are specifically designed to meet the stringent drug and alcohol testing requirements mandated by the U.S. Department of Transportation (DOT) for safety-sensitive positions in the transportation industry, ensuring compliance and public safety.

Our Drug Testing Partners