Missouri Drug Testing

Substance abuse can rip apart businesses, communities, and families. US Drug Test Centers offers alcohol and drug testing to employers, employees, and other residents across Missouri.

Keep reading to learn more about our Missouri drug testing services.

Our testing locations do not accept payment and require a drug test order form at the time of testing. Please click the "Order a Test" button to order your test. Once your order has been processed, your drug test order form will be emailed to you. Testing options may vary on a site by site basis. Additional fees may apply depending on your location.

Committed to Accuracy

We only work with SAMHSA-certified laboratories and have all test results confirmed by a medical review officer.

Unparalleled Convenience

With drug testing locations spread throughout Missouri, you never have to go far to find us. For speedy results, we offer instant urine drug testing and on-site mobile testing.

Endless Variety

We can screen for dozens of illicit substances via hair, urine, and breath. Additionally, we have hundreds of drug test panels to choose from.

588 Testing locations in Missouri

2055 S Fremont Ave

Springfield Missouri 65804

Phone: 866-566-0261

608 Old Route 66

Saint Robert Missouri 65584

Phone: 866-566-0261

108 W 15Th St

Caruthersville Missouri 63830

Phone: 866-566-0261

1065 State Highway 248

Branson Missouri 65616

Phone: 866-566-0261

17110 Mo-87

Boonville Missouri 65233

Phone: 866-566-0261


583 more location(s) available in Missouri

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Local Reviews

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Review by G.D.
on March 13, 2024

"Your company does everything well"

Review by J.J.E.
on August 24, 2023

"Love that you always get a live person that you can understand and is willing to help. They go above and beyond to help you get things figured out in a timely manner."

Review by M.J.
on August 24, 2023

"Very professional staffing"

Review by V.D.
on August 18, 2023

"The associates are very helpful and courteous whenever I call with questions. They walk me through the procedures."

Review by R.S.
on April 5, 2023

"Received a phone call with A LOT of information. The walk through the website was nice, but a written instruction sheet would be nice."

Review by D.G.
on March 29, 2023

"Easy to contact.. Every time I needed to add an employee,are order a drug test they took care of it immediately!! No long wait time..An the people is very friendly an helpful.. Thank y’all so much"

Review by D.H.
on March 14, 2023


US Drug Test Centers

US Drug Test Centers

We are your complete drug-free workplace solution for employers. We provide drug testing for all reasons such as pre-employment, random, reasonable suspicion, post-accident, and return to duty. We have a state-of-the-art cloud-based software that allows you to order drug testing 24/7, store all drug test results and chain of custody forms (forever), and you can see the status of all completed drug testing. We have random drug and alcohol testing consortiums and follow all DOT rules and regulations to direct your company in the right direction to stay in compliance. We can create drug-free workplace policy manuals specific to your company's needs, and we provide online trainings. Our online trainings are perfect for company Supervisors to learn what signs to look for if someone might be under the influence. We also have trainings that explain what Supervisors should know about the DOT rules and regulations in regards to the drug and alcohol testing program. We are a part of the Drug and Alcohol Testing Industry Association (DATIA), and we always stay up to date with all drug testing-related rules and regulations. If you have any questions about state-specific laws regarding drug and alcohol testing, please contact our office and one of our team members will be glad to help you. If your company would like more information regarding setting up a corporate account you can set up an account online or contact us at 866-566-0261.

Frequently Asked Questions About Missouri Drug Testing

This material is intended for informational purposes only and should not be relied upon for legal guidance. State & local laws change frequently and vary greatly. These are state & local laws and do not over rule the federal Department of Transportation laws & policies. Readers are advised to consult with their legal counsel or industry experts before acting based on this information. Last Updated May 2023

Missouri Drug Testing FAQs

Do employers in Missouri need to comply with mandatory state-specific rules when drug & alcohol testing?
No. Missouri does not have any mandatory drug testing statutes or regulations but it is recommended.
Is a Drug-Free Workplace policy required in Missouri?
No, however, employers are strongly encouraged to have a written policy in place (Policy is specifically required to comply with the Missouri’s voluntary law).
Are employers in Missouri able to use drug screening for any other claim defenses or state-specific financial benefits?
Yes. Employers may be able to leverage a ‘Rebuttable Presumption of Intoxication’ defense to a Workers’ Compensation Claim, based on a positive drug test result. A positive drug test may also make an employee ineligible for unemployment compensation. Employers wishing to leverage either of these benefits must voluntarily comply with very detailed program rules.
What are some nuances of the voluntary Drug-Free Workplace Program requirements in Missouri?
Employers are required to have a written company policy and provided a specific posted warning that a positive test may result in suspension or termination of employment. All testing must comply with 49 CFR Part 40 requirements. Employers are required to use an HHS certified laboratory.
Does Missouri authorize marijuana (THC) or cannabidiol (CBD) use?
Yes. Missouri authorizes the medical use of marijuana and cannabidiol for limited medical conditions. The law includes language that protects employers from adverse action by an authorized medical marijuana user.
Can I be fired or lose a job offer in Missouri if I fail a drug test?
In Missouri, if you test positive on a drug test it cannot be grounds for termination or a rescinded job offer.
What are the medical and recreational marijuana-related rules in Missouri?
In Missouri, medical and recreational marijuana use is considered legal and cannot be used against you if you test positive, unless you are in a safety sensitive position.

Drug Testing Stats - Missouri

Drug and Alcohol Abuse Statistics from Missouri

Last Updated: March 1, 2024

  • In Missouri, 342 patients are in the hospital dealing with substance abuse problems resulting in rehab.
  • In Missouri, a study was done on 25% of most active drinkers and found that 4.8 binge drink each month.
  • In Missouri, excessive alcohol drinking has been attributed to approximately 2,877 deaths each year.
  • In 2022, a study was done to show that $6.215 billion or $2.47 per drink was spent on alcohol in Missouri, which was much higher than other years due to inflation.
  • 2.25% of people in Missouri died from a drug overdose.
  • In Missouri there were 9,064 registered employers in the FMCSA Clearinghouse and out of the 9,064 registered, there were 5,776 violations.

Drug and Alcohol Abuse in Missouri

Substance abuse in Missouri is a steady problem. Data tells us that 18.90% of adults 18 years of age and older binge drink once a month, if not more. They see 1,583 fatalities every single year due to drug overdoses. Specifically, every year, opioid overdoses kill about 132 individuals in the state.

Costs Associated With Rehab

There are approximately 293 functioning rehab facilities in Missouri, but the cost is steep. For example, inpatient rehabilitation is $56,782 per individual, which can be incredibly prohibitive. Outpatient rehabilitation typically costs about $1,710.


  1. The National Survey on Drug Use and Health (NSDUH), conducted annually by the Substance Abuse and Mental Health Services Administration (SAMHSA)
  2. Provisional Multiple Cause of Death database contains mortality and population for U.S. counties.
  3. Alcohol Use in the United States: Age Groups and Demographic Characteristics
  4. United States Department of Transportation - FMCSA Drug and Alcohol Clearinghouse - December 2023 Report

Workplace Drug Testing for Non-DOT and DOT Companies

Drug use at work costs employers tens of billions of dollars every year due to lost productivity, increased employee turnover, and a spike in on-the-job accidents and crime. This is why workplace drug testing in Missouri is so important.

We work with Missouri employers of both Department of Transportation (DOT) and non-DOT companies to keep their businesses drug-free:

  • We'll manage all of your drug testing, including random drug testing, reasonable suspicion testing, pre-employment testing, post-accident testing, and return-to-duty drug screening.

  • US Drug Test Centers will train your staff, including your designated employer representative (DER), to manage your drug testing program.

  • We'll craft your drug-free workplace policy, which outlines how you go about drug testing current employees, what happens if someone receives a positive drug test, how you avoid bias in random testing, how you address marijuana use, what disciplinary action looks like, and more.

  • We conduct background checks, which you can order and review electronically.

If you're a company or owner-operator employed by the DOT, we'll ensure that you abide by local and federal law so that you can pass a DOT audit at any time. This is especially important for individuals working safety-sensitive jobs.

Court-Ordered Drug Testing

If you're an individual in need of a court-ordered drug test in Missouri, we offer legal testing for child custody, probation, and DUI cases. Simply order a test online, or contact us with any questions.

St. Louis, Missouri

Why US Drug Test Centers?

What makes us the top choice for all of your drug screening needs?

We Prioritize Accuracy Above All Else

All of our test results are verified by a medical review officer (MRO), who is a licensed physician. This is important because, for example, should an employee test positive but have concerns that it was triggered by their prescription medication, an MRO can confirm this.

Additionally, we only partner with SAMHSA-certified labs.

We Offer the Largest Variety of Testing Options

As we mentioned, we can provide all types of drug screening for Missouri employers, including pre-employment drug testing and random drug testing. We can screen via urine, hair, and breath.

Furthermore, we can test for a large array of substances, including recreational marijuana/medical marijuana, opioids, suboxone, steroids, ecstasy, PCP, barbiturates, cocaine, Rohypnol, and even heavy metals.

We Provide Speedy and Convenient Drug Testing

With more than 20,000 drug testing locations across the country, we're never more than a short drive away.

If you need Missouri drug testing in a hurry, consider instant/POCT drug screening, where negative results are delivered the same day. Additionally, we offer mobile on-site drug testing, where a collector will meet you (or your employee) within two hours to begin the collection process.

Car driving in the snow

Order Your Drug Test Today

We're proud to help Missouri employers, employees, and other residents help keep drugs and alcohol at bay.

Whether you need assistance writing your employer's policy, you're a parent concerned that your child is using recreational marijuana, you're a DOT owner-operator wanting to follow federal law, or you have other drug screening needs entirely, we're here to help!

Order your test online, find a testing center near you, or contact us with any questions.

Available Collection Types

US Drug Test Centers offers the full range of collection types, including urine, hair and breath samples, each with its own advantages and applications for accurate substance screening.

Legal Drug Testing

Legal drug testing is a critical procedure often mandated by employers, law enforcement agencies, and organizations to ensure compliance with regulations and maintain safety in various settings. US Drug Test Centers can help you with your testing needds.

DOT Testing Services

DOT Testing Services are specifically designed to meet the stringent drug and alcohol testing requirements mandated by the U.S. Department of Transportation (DOT) for safety-sensitive positions in the transportation industry, ensuring compliance and public safety.

Laboratory Testing Services

Looking for nationwide laboratory testing? US Drug Test Centers has partnered with eNational Testing to offer laboratory testing such as blood titers (MMR, Varicella, Hep B), QuantiFERON (TB Blood) Testing, Mens & Womens health panels, allergy testing and much more! You can simply order a health lab test or panel online 24/7 and go in for testing the same day at over 2,700 locations nationwide.

Scheduling your preventative health laboratory testing in Missouri here.

Our Drug Testing Partners